Lipid Controls
Medchemexpress LLC DODMA | 104162-47-2 | 99.6% | 620.09 | 100 MG
DODMA is a cationic lipid used to prepare lipid nanoparticles for drug delivery. Its unique pH-titratable head group maintains neutrality at physiological pH, aiding systemic circulation. Upon encountering the acidic environment of endosomes, the head group protonates, facilitating membrane fusion and promoting nucleic acid release.
- Cationic lipid for lipid nanoparticle preparation
- Used in drug delivery applications
- pH-titratable head group for systemic circulation
- Promotes fusion with endosome membrane
- Facilitates nucleic acid release
Avanti Polar Lipids GM1 IN POWDER 1MGGM1 IN POWDE
GM1 Ganglioside (Brain, Ovine-Sodium Salt). 37758-47-7
Medchemexpress LLC Dspe-peg2000-crgdkgpdc (disulfide bridge:Cys1-Cys9) | 95.0% | 2000 (Average) | 25 MG
DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and an αv-integrins targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and is then proteolytically cleaved in the tumor to produce CRGDK/R, which interacts with neuropilin-1. This compound has tumor-targeting and tumor-penetrating properties and can be used for agent delivery.
- Irgd peptide binds to αv-integrins.
- Proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1.
- Possesses tumor-targeting and tumor-penetrating properties.
- Can be used for agent delivery.
- Used to construct nanomicelles for targeted delivery of salinomycin to intervene in liver cancer cells and cancer stem cells.
- Used to construct a tumor-penetrating peptide liposome that exhibits antitumor effects, including a significant reduction in tumor volume and an increase in body weight and spleen index.
Cayman Chemical Lyso-PAF C-16 10mg
Lyso-PAF C-16 can be formed by either the action of PAF-AH on PAF C-16,{2626} or by the action of a CoA-independent transacylase on 1-O-hexadecyl-2-acyl-glycerophosphocholine.{240,2098} Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway{939} or selective acylation with arachidonic acid by a CoA-independent transacylase.{2101}
Cayman Chemical DLIn-MC2-DMA 5mg
An ionizable cationic lipid; has been used in the formation of LNPs; LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding FVII reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg)
Cayman Chemical 1 3DIstearoyl2oloyl Glyce 25mg
A triacylglycerol; has been found in Kpangnana, Chinese tallow, and cocoa butters; increases the phagocytic function of reticulo-endothelial cells in mice at 5 and 10 mg per animal
Avanti Polar Lipids 18 1-D7 LYSO PC
18 1-d7 Lyso PC1-oleoyld7-2-hydroxy-sn-glycero-3-phosphocholine1mg
Cayman Chemical DLIn-KC2-DMA 1mg
An ionizable cationic lipid (pKa = 6.7); has been used in the formation of LNPs encapsulating siRNA or plasmid DNA for use in vitro and in vivo; LNPs containing DLin-KC2-DMA selectively accumulate in the liver after i.v. or i.m. administration in mice or localize to the retinal pigment epithelium and Müller glia after subretinal administration; DLin-KC2-DMA-containing LNPs encapsulating F7-targeted siRNA reduce serum Factor VII levels in mice; DLin-KC2-DMA-containing LNPs encapsulating AR-targeted siRNA decrease serum PSA and tumor androgen receptor levels in an LNCaP prostate cancer mouse xenograft model
Medchemexpress LLC DLin-M-C4-DMA | 1226909-66-5 | C44H81NO2 | 1 ML
DLin-M-C4-DMA, also known as Compound MC4, is a cationic lipid. It is primarily used for the effective delivery of nucleic acids in various research applications. This product is provided as a colorless to light yellow liquid.
- Used for delivery of nucleic acids
- Functions as a cationic lipid
- Targets liposomes
- Involves the metabolic enzyme/protease pathway
- Appears as a colorless to light yellow liquid
![Avanti Polar Lipids [16-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino] palmitic acid | 2260669-56-3 | 1mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/ENCOMPASSDEFAULTIMAGE.JPG-250.jpg)
Avanti Polar Lipids [16-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino] palmitic acid | 2260669-56-3 | 1mg
[16-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino] palmitic acid | Purity: 99%2260669-56-3 | 1mg